Comparison of ketorolac versus paracetamol for pain control

Admin Dental Press

Edition V01N01 | Year 2015 | Editorial Original Article | Pages 28 to 35

José Rodrigues Laureano Filho, Paul Maurette O’brien, Marvis Allais, Patricio José De Oliveira Neto

Introduction: The surgical removal of impacted third molars has been widely used as a dental model in several studies comparing analgesic drugs, as well as the occurrence of adverse effects with the use of such medicines. Methods: This study was conducted in order to compare the analgesic efficacy of ketorolac tromethamine 10 mg with paracetamol 750 mg in the control of postoperative pain after impacted lower third molars surgery, as well as observe the occurrence of adverse effects with the use of ketorolac in patients of spontaneous demand of the School of Dentistry of Pernambuco (FOP). A total of 15 patients presenting lower third molars with the same type of inclusion, and which were submitted to surgical removal of these teeth under local anesthesia on two occasions, were included in this study. Each patient acted as their own control, and after surgery would make use of tablets of ketorolac or paracetamol for pain control. In a questionnaire, patients would register the level of pain on a visual analogue scale (VAS), as well as the total amount of tablets necessary for the control of pain and the side effects that they occasionally presented. Results: In the two moments of evaluation, 24 and 48 h, the number of tablets taken and the pain intensity assessed by VAS did not show any statistically significant difference (P < 0.05). Conclusion: Both ketorolac and paracetamol proved to be effective in pain control after surgery in which the first presented a greater number of adverse effects in comparison to the second. Ketorolactromethamine, Unerupted tooth, Postoperativepain, Analgesia,

Laureano Filho JR, O’Brien PM, Allais M, Oliveira Neto PJ. Comparação entre cetorolaco e paracetamol na dor pós-operatória. J Braz Coll Oral Maxillofac Surg. 2015 jan-abr;1(1):28-35. DOI:

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