Comparative study of dipyrone and paracetamol pain control after third molar extraction

Admin Dental Press

Edition V04N02 | Year 2018 | Editorial Interview | Pages 32 to 37

Gabriela Mayrink, Bruno Nicolai, Jorge Pedro Aboumrad Júnior

Pain is an unpleasant sensory experience, a stimulus known throughout the world; however, is subjective in nature and quite unique in the majority of patients undergoing surgery in the oral cavity. Analgesics can be used in oral surgery postoperative, being dipyrone, an acetaminophen the most common. In the present study, 20 patients were selected from the Department of Oral and Maxillofacial Surgery and Traumatology of the Faculdades Integradas Espírito Santenses (FAESA), which, according to the inclusion criteria, would undergo extraction of third molars. All patients were pre-operatively treated with 4mg dexamethasone 2 hours before the procedure. Each extraction was performed on different days and dipyrone 500mg or acetaminophen 750mg was selected for the postoperative. A visual analog scale was used by the patient to indicate the amount of postoperative pain. Analysis of evaluated quantitative criteria was conducted, such as effectiveness of the drug, the opinion of patients and duration of the pain, and in both groups an analgesic advantage of dipyrone was observed. Dipyrone 500mg demonstrated superior analgesic efficacy than acetaminophen 750mg, in controlling postoperative pain in third molar surgery.

Pain, Surgery, oral, Analgesia,

Mayrink G, Nicolai B, Aboumrad Júnior JP. Comparative study of dipyrone and paracetamol pain control after third molar extraction. J Braz Coll Oral Maxillofac Surg. 2018 May-Aug;4(2):32-7. DOI:

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